Reuters has published an article entitled, "Twitter Goes Literary With Ulysses Performance." The article states, "Bogost and McCarthy (two literary enthusiasts) registered 54 of the novel's characters as Twitter users and adapted the chapter in a large series of 140-character or less first-person statements, using a specially created software to automate a performance." They specifically worked with Chapter 10, Wandering Rock.
What a wonderful idea!!
Literature teachers could ask students to recreate literary scenes using Twitter. To create a private Twitter network, students could simply develop private hash-tags. Teachers could choose how closely they wanted students to follow the prose of the text. Personally, I'd prefer to challenge students to simply use the text as a starting point and then creatively expand upon it.